NCT01537224

Electrophysiological Activity of the Subthalamic Nucleus During the Processing of Emotional and Motivational Information

Study of the Electrophysiological Activity of the Subthalamic Nucleus During the Processing of Emotional and Motivational Information in Patients With Parkinson's Disease

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 25 (estimated)
• Sponsor: Rennes University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The role of the basal ganglia in the processing of information with emotional or motivational content has been demonstrated by several lesion and functional imaging studies in humans and animals. Deep brain stimulation surgery provides an opportunity to study these structures in humans in electrophysiological terms. The aim of this study is to investigate modifications in the electrophysiological activity of the subthalamic nucleus (STN) during the perception of auditory and visual stimuli with emotional or motivational connotations in patients with Parkinson's disease who have just undergone implantation of a deep brain stimulator in the STN.

Conditions

• Parkinson

Interventions

Type	Name	Description
OTHER	Measure of the electrophysiological activity of the subthalamic nucleus	Local field recording of the subthalamic nucleus by mean of externalized electrodes in the immediate postoperative periode.

Timeline

• Start date: 2011-09-01
• Primary completion: 2013-09-01
• Completion: 2013-12-01
• First posted: 2012-02-23
• Last updated: 2012-12-03

Locations

1 site across 1 country: France