NCT01534572

Significance of Synbiotics on Inflammation and Proliferation of Colonic Mucosa

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: Region Skane · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

There is a constant exchange between the gut epithelium and lumen, including microbial interplay. The aim of this study was to investigate dietary test products on inflammatory proliferation markers in the gut, and thereby if the products had positive effects in the gut as well as in other parts of the body. The hypothesis was that the test products would reduce the inflammatory and proliferation activity of the gut epithelium by fermentation of normal food products and by converting dietary phenolic compounds into anti-inflammatory substances.

Conditions

• Inflammation

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Lactobacillus	Intervention (2 weeks) with a strain of Lactobacillus
DIETARY_SUPPLEMENT	Bifidobacterium	Intervention (2 weeks) with a strain of Bifidobacterium

Timeline

• Start date: 2006-01-01
• Primary completion: 2006-03-01
• Completion: 2012-02-01
• First posted: 2012-02-16
• Last updated: 2012-02-16