NCT01533688

Study of Efficacy and Tolerability of Various Bowel Preps in Diabetic Patients

Efficacy and Tolerability of Various Bowel Preparations in Diabetic Patients: A Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 212 (actual)
• Sponsor: University of Oklahoma · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Accepted

Summary

Poor bowel preparation and patient intolerance of the procedure are the most important factors contributing to the limitation of colonoscopy. Inadequate bowel cleansing results in incomplete testing, increased potential to miss lesions, increased cost, and decreased patient satisfaction. The investigators hope to gain better insight into which bowel preparation works best in diabetic patients and hence would increase patient satisfaction, tolerability of the bowel preparation and decrease overall costs. The investigators will investigate which bowel preparation for colonoscopy will work optimally in diabetic patients using three different regimens.

Conditions

• Diabetes Mellitus

Interventions

Type	Name	Description
DRUG	Golytely (polyethylene glycol electrolyte lavage solution) and placebo	4 liters of polyethylene glycol electrolyte lavage solution (PEG-ELS-(GoLytely))+ placebo given the evening prior to the colonoscopy
DRUG	split dose of Golytely (polyethylene glycol electrolyte lavage solution) + placebo	split dose (2 L taken the evening before and 2 L taken the morning of the colonoscopy) of 4 liters Golytely + placebo
DRUG	split dose of Golytely (polyethylene glycol electrolyte lavage solution) and bisacodyl	split dose ( 2 L taken the evening before and 2 L taken the morning of the colonoscopy) of 4 liters of Golytely + bisacodyl 10 mg

Timeline

• Start date: 2011-10-01
• Primary completion: 2016-10-01
• Completion: 2016-10-01
• First posted: 2012-02-15
• Last updated: 2018-09-07
• Results posted: 2018-08-08

Locations

1 site across 1 country: United States