NCT01533129

The Effect of Testosterone Replacement on Endothelial Dysfunction, Inflammation and Insulin Resistance in Male Hypogonadotrophic Hypogonadism

Phase 4 Study That Evaluates the Effects of Two Different Testosterone Replacement Regiments on Endothelial Dysfunction, Inflammation and Insulin Resistance in Male Subjects With Hypogonadotrophic Hypogonadism.

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 106 (actual)
• Sponsor: Gulhane School of Medicine · Academic / Other
• Sex: Male
• Age: 18 Years – 26 Years
• Healthy volunteers: Not accepted

Summary

The study searched for answers to two questions 1. What is the effect of testosterone replacement therapy on endothelial dysfunction, inflammation and insulin resistance? 2. Regarding the above parameters, is there any difference between daily transdermal testosterone implementation and intramuscular injection performed in three weeks.

Conditions

• Hypogonadotrophic Hypogonadism

Interventions

Type	Name	Description
DRUG	Testogel 50 mg transdermal gel	50mg testosterone gel implementation on every night
DRUG	Testosterone 250mg injection	The testosterone 250mg ester IM injections performed in three weeks.

Timeline

• Start date: 2008-08-01
• Primary completion: 2011-04-01
• First posted: 2012-02-15
• Last updated: 2020-07-22

Locations

1 site across 1 country: Turkey (Türkiye)