NCT01531491

Effects of Hypercapnia on Emergence From General Anesthesia Under Propofol

Effects of Hypercapnia on Emergence From General Anesthesia Under Propofol: a Pilot Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: DongGuk University · Academic / Other
• Sex: All
• Age: 20 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

Hypercapnia derives increase of cerebral blood flow and cardiac output. It means that the rate of propofol elimination from the brain and the blood will be increased and the patient will awake more quickly. There has been no study about the effects of hypercapnia. The investigators will evaluate hypercapnia's effects on the recovery time from propofol anesthesia.

Conditions

• Anesthesia, Intravenous
• Anesthesia Recovery Period

Interventions

Type	Name	Description
PROCEDURE	Rebreathing tube	750 ml rebreathing tube will be connected between the corrugated tube and the tracheal tube of a patient. Target partial pressure of the end-tidal carbon dioxide is 50 mmHg.
PROCEDURE	No rebreathing tube (Nothing)	750 ml rebreathing tube will not be connected between the corrugated tube and the tracheal tube of a patient. Target partial pressure of the end-tidal carbon dioxide is 30 mmHg.

Timeline

• Start date: 2012-01-01
• Primary completion: 2013-06-01
• Completion: 2013-06-01
• First posted: 2012-02-13
• Last updated: 2015-02-16

Locations

1 site across 1 country: South Korea