NCT01531192

Comparison of Lactobacillus Reuteri and Nystatin Prophylaxis on Candida Colonization and Infection in Very Low Birth Weight Infants

Zekai Tahir Burak Maternity Teaching Hospital, Ankara/Turkey

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 300 (actual)
• Sponsor: Zekai Tahir Burak Women's Health Research and Education Hospital · Academic / Other
• Sex: All
• Age: 1 Day – 6 Months
• Healthy volunteers: Not accepted

Summary

Probiotics are favorable microorganisms that regulate the flora of the gastrointestinal system and stimulate the immune system. Lactobacillus reuteri was shown to reduce candida colonization. The objective of this study is to evaluate the efficacy of prophylactic Lactobacillus reuteri in reducing the candida colonization and infection in very low birth weight infants.

Conditions

• Very Low Birth Weight Infants

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Lactobacillus reuteri	Lactobacillus reuteri 100 million CFU/day for 3 months
DRUG	Nystatin	50000 unit/3 times a day, both for orally and by orogastric route

Timeline

• Start date: 2012-06-01
• Primary completion: 2013-04-01
• Completion: 2013-04-01
• First posted: 2012-02-10
• Last updated: 2013-07-16

Locations

1 site across 1 country: Turkey (Türkiye)