NCT01530165

(Pakistan Diabetes Prevention Program PDPP)

A Translation Randodomized Trial of Culturally Specific and Cost Effective Life Style Intervention for the Prevention of Type 2 Diabetes in Pakistan

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,564 (actual)
• Sponsor: Aga Khan University · Academic / Other
• Sex: All
• Age: 30 Years – 64 Years
• Healthy volunteers: Accepted

Summary

The Karachi-based Pakistan Diabetes Prevention Study aims to address key issues in the prevention of type 2 diabetes. Approximately 20,000 people From four communities will be screened for diabetes risk factors using a non-invasive diabetes risk-score system. Those found to be at increased risk will be given an oral glucose tolerance test. People who, after the oral glucose tolerance test, are identified as having prediabetes or normal but with risk factors such as raised BMI and/or history of hypertension will have the opportunity to take part in the Pakistan Diabetes Prevention Study lifestyle intervention. This consists of culturally adjusted preventive strategies focusing on diet and physical activity in real-life settings. Another important aspect of this trial will be to assess the impact of urban planning on the prevalence of obesity and diabetes.

Detailed description

The aim of this study is to translate the life style intervention project to prevent diabetes into real life settings in Karachi, Pakistan, home to one sixth of the world's population.

Conditions

• Prediabetic State & High Risk Individuals on the Basis of Diabetes Risk Score

Interventions

Type	Name	Description
BEHAVIORAL	Life style intervention	The main goals of intervention will focus mainly on: Weight reduction ≥ 5% , moderate intensity physical activity ≥ 30 min daily, dietary fat \<30 proportion of total energy, saturated fat \<10%, Fiber ≥ 15g/1,000 kcal There will be 9 sessions during the two years course of follow-up

Timeline

• Start date: 2011-12-15
• Primary completion: 2017-06-30
• Completion: 2017-06-30
• First posted: 2012-02-09
• Last updated: 2024-07-29

Locations

1 site across 1 country: Pakistan