NCT01529346

Efficacy Of PF-05089771 In Treating Postoperative Dental Pain

A Randomized, Double-blind, Double-dummy, Parallel Group, Placebo Controlled Study Assessing The Efficacy Of Single Doses Of Pf-05089771 For The Treatment Of Postoperative Dental Pain Using Ibuprofen 400 Mg As Positive Control

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 235 (actual)
• Sponsor: Pfizer · Industry
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Not accepted

Summary

The objective of this study is to evaluate the overall pain relief of a single dose of PF-05089771 against placebo following third molar extraction.

Conditions

• Postoperative Dental Pain

Interventions

Type	Name	Description
DRUG	PF-05089771	A single dose of PF-05089771 1600 mg oral solution administered once to the subject on Day 1 postoperatively
OTHER	Placebo	Placebo tablets for ibuprofen: 2 X 200 mg placebo tablets administered orally once to the subject on Day 1 postoperatively
DRUG	PF-05089771	A single dose of PF-05089771 450 mg oral solution administered once to the subject on Day 1 postoperatively
OTHER	Placebo	Placebo tablets for ibuprofen: 2 X 200 mg placebo tablets administered orally once to the subject on Day 1 postoperatively
DRUG	PF-05089771	A single dose of PF-05089771 150 mg oral solution administered once to the subject on Day 1 postoperatively
OTHER	Placebo	Placebo tablets for ibuprofen: 2 X 200 mg placebo tablets administered orally once to the subject on Day 1 postoperatively
DRUG	Ibuprofen	2 X 200 mg tablets of ibuprofen administered orally once to the subject on Day 1 postoperatively
OTHER	Placebo	Placebo solution for PF-05089771: A single dose of Placebo solution administered once to the subject on Day 1 postoperatively
OTHER	Placebo	Placebo solution for PF-05089771:A single dose of Placebo solution administered once to the subject on Day 1 postoperatively
OTHER	Placebo	Placebo tablets for Ibuprofen: 2 X 200 mg placebo tablets administered orally once to the subject on Day 1 postoperatively

Timeline

• Start date: 2011-12-12
• Primary completion: 2012-06-25
• Completion: 2012-06-25
• First posted: 2012-02-08
• Last updated: 2018-06-01
• Results posted: 2018-06-01

Locations

3 sites across 1 country: United States