NCT01528436

Umbilical Cord Blood Therapy for Cerebral Palsy

Umbilical Cord Blood Therapy for Cerebral Palsy: a Randomized,Double-blind, Placebo-controlled Trial

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 37 (actual)
• Sponsor: MinYoung Kim, M.D. · Academic / Other
• Sex: All
• Age: 6 Months – 20 Years
• Healthy volunteers: Not accepted

Summary

This randomized controlled study aims to evaluate the efficacy of umbilical cord blood therapy for children with cerebral palsy.

Detailed description

Cerebral palsy is a disorder of movement and posture resulted from a non-progressive lesion or injury of the immature brain. It is a leading cause of childhood onset disability. Many experimental animal studies have revealed that umbilical cord blood is useful to repair neurological injury in brain. On the basis of many experimental studies, umbilical cord blood is suggested as a potential therapy for cerebral palsy.

Conditions

• Cerebral Palsy

Interventions

Type	Name	Description
BIOLOGICAL	Umbilical Cord Blood Infusion	The subjects will be undertaken allogeneic umbilical cord blood infusion intravenously or intraarterially under non-myeloablative immunosuppression.
OTHER	Placebo Umbilical Cord Blood	Placebo Umbilical Cord Blood that resembles cord blood in appearance was designed.
OTHER	Active Rehabilitation	All subjects should participate in active rehabilitation. They will receive two physical and occupational therapy sessions per day. Post discharge, each participant should continue to receive rehabilitation therapy at least 3 days per week until the study completion.

Timeline

• Start date: 2012-02-01
• Primary completion: 2012-07-01
• Completion: 2012-07-01
• First posted: 2012-02-08
• Last updated: 2012-07-18

Locations

1 site across 1 country: South Korea