NCT01528202

Tart Cherries and Melatonin Content

Effect of Tart Cherry Juice (Prunus Cerasus) on Melatonin Levels and Sleep Quality

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Northumbria University · Academic / Other
• Sex: All
• Age: 18 Years – 39 Years
• Healthy volunteers: Accepted

Summary

The aim of this investigation was to examine the effects of tart Montmorency cherry juice on urinary 6-sulfatoxymelatonin and sleep quality using a double-blind, placebo-controlled, cross-over design.

Detailed description

The aim of the study is to examine the efficacy of tart cherry juice on sleep quality, quantity, and timing. Naturally circulating melatonin is instrumental in regulating sleep/wake schedules. Tart Montmorency cherries (Prunus Cerasus) contain high levels of melatonin and may be a useful intervention to supplement for realignment of circadian phase and by increasing the robustness of circadian amplitude. In normal healthy adults, with experimentally induced phase advanced circadian misalignment, the administration of a 3mg supplement of melatonin significantly increased sleep architecture characteristics. In this study we want to examine the efficacy of tart cherry juice in increasing urinary levels of melatonin and the subsequent impact this will have on sleep parameters.

Conditions

• Sleep

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Cherry juice	30 mLs preceding morning meal and 30 mLs preceding evening meal each day for 7 days.
DIETARY_SUPPLEMENT	Fruit juice cordial	fruit flavoured juice concentrate

Timeline

• Start date: 2010-04-01
• Primary completion: 2011-02-01
• Completion: 2011-06-01
• First posted: 2012-02-07
• Last updated: 2012-02-07

Locations

1 site across 1 country: United Kingdom