NCT01524120

Endoscopy and Endomicroscopy for Assessment of Mucosal Healing in Inflammatory Bowel Disease (IBD)

• Status: Withdrawn
• Phase: —
• Study type: Observational
• Enrollment: 0 (actual)
• Sponsor: University of Erlangen-Nürnberg Medical School · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

Inflammatory bowel disease (IBD) encompasses two major forms of chronic intestinal disorders, Crohn's disease and ulcerative colitis (UC). Diagnosis is based on several macroscopic and histologic features including patterns of inflammation, crypt abscesses and granulomas. Confocal laser endomicroscopy (CLE) is rapidly emerging as a valuable tool for gastrointestinal endoscopic imaging, enabling the endoscopist to obtain an "optical biopsy" of the gastrointestinal mucosa during the endoscopic procedure. The main objective of this study is to determine endoscopic and endomicroscopic features of mucosal healing in patients with IBD.

Conditions

• Inflammatory Bowel Disease
• Crohn's Disease
• Ulcerative Colitis

Interventions

Type	Name	Description
DEVICE	Endoscopy (EPK-i, Pentax, Tokyo, Japan)	Patients will undergo white-light endoscopy. Any mucosal lesions will be recorded and findings will be compared to histopathological and clinical results.
DEVICE	Endomicroscopy (iCLE, Pentax, Tokyo, Japan)	Patients will undergo endomicroscopy. Data will be recorded and findings will be compared to histopathological and clinical results.
DEVICE	Endoscopy (EPK-i, Pentax, Tokyo, Japan)	Patients will undergo white-light endoscopy. Any mucosal lesions will be recorded and findings will be compared to histopathological and clinical results.
DEVICE	Endomicroscopy (iCLE, Pentax, Tokyo, Japan)	Patients will undergo endomicroscopy. Data will be recorded and findings will be compared to histopathological and clinical results.

Timeline

• Start date: 2012-04-01
• First posted: 2012-02-01
• Last updated: 2020-12-14

Locations

1 site across 1 country: Germany