NCT01523028

Influence of Breakfast Consumption on Chlorogenic Acid Metabolism in Humans

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 14 (actual)
• Sponsor: Société des Produits Nestlé (SPN) · Industry
• Sex: All
• Age: 20 Years – 44 Years
• Healthy volunteers: Accepted

Summary

Data and knowledge gathered on bioavailability of coffee phenolics is becoming more and more important, hence underlying the importance of better understanding the fate of these potential health promoting antioxidants. However, some analytical barriers as well as some key aspects of metabolism still remain to be fully elucidated to get the full picture of coffee metabolism and bioavailability. One aspect addressed in the present study is the impact of food matrix in modulating absorption, plasma appearance and urinary excretion of coffee bioactives.

Conditions

• Healthy

Interventions

Type	Name	Description
OTHER	Soluble Coffee	Amounts of chlorogenic acids will be normalized to body weight (3.1 mg CA / kg BW). Coffee will be reconstituted in 200 mL hot water and consumed 3 times in a row (min 1-week interval), alone or with a breakfast: * 200 mL coffee or * 200 mL coffee + 2 bread rolls + honey * 200 mL coffee + 1 bread roll + peanut butter

Timeline

• Start date: 2011-09-01
• Primary completion: 2012-12-01
• Completion: 2012-12-01
• First posted: 2012-02-01
• Last updated: 2013-06-05

Locations

1 site across 1 country: Germany