NCT01521039

Assessment of MicroRNA Expression in Acute Graft-versus-Host Disease

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 259 (actual)
• Sponsor: Ohio State University Comprehensive Cancer Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Assessment of MicroRNA Expression in Acute Graft-versus-Host Disease (GVHD).

Detailed description

The purpose of this study is to examine whether the expression levels of a novel class of molecules, called microRNAs, are associated with acute graft-versus-host disease frequency and severity. Acute graft-versus-host disease is a Acute GVHD is a medical condition that can become very serious. It happens when the donor cells attack and damage your tissues after transplant.

Conditions

• Acute Graft-versus-Host Disease
• Allogeneic Stem Cell Transplant

Interventions

Type	Name	Description
PROCEDURE	Blood samples	2-3 tablespoons of blood weekly for the first 100 days (about 14 weeks) following allogeneic transplant. In addition a blood sample will be obtained before starting the chemotherapy or radiation regimen for the transplant, in the day of the transplant and if your doctor suspects that you have acute graft-versus-host disease.

Timeline

• Start date: 2012-02-20
• Primary completion: 2024-12-30
• Completion: 2024-12-30
• First posted: 2012-01-30
• Last updated: 2025-01-20

Locations

1 site across 1 country: United States