NCT01520974

Effect of an Oral Probiotic Tablet on Oral Bacteria and Clinical Measurements (ProBiora3)

ProBiora3 Oral Care Probiotics Usage

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 48 (estimated)
• Sponsor: Oragenics, Inc. · Industry
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine if an oral probiotic tablet taken once a day for twelve weeks can decrease the numbers of bacteria that are associated with tooth decay and gum disease in a dentally healthy, young adult population.

Detailed description

There are over 500 types of bacteria in the mouth. Most of these bacteria do not cause disease. However, some mouth bacteria can cause tooth decay and gum disease. The purpose of a probiotic tablet for the mouth is to put known healthy bacteria in the mouth. This study will compare the effect of the probiotic tablet on the levels of harmful or disease causing bacteria in the mouth to a placebo tablet that does not contain any probiotic bacteria.

Conditions

• Oral Health

Interventions

Type	Name	Description
OTHER	ProBiora3 mints	Probiotic mint tablet taken once daily for 12 weeks containing ProBiora3, a combination of three known healthy bacteria
OTHER	Placebo tablet	Mint tablet taken once daily for 12 weeks without the ProBiora3 combination of three known healthy bacteria

Timeline

• Start date: 2012-01-01
• Primary completion: 2012-08-01
• First posted: 2012-01-30
• Last updated: 2012-05-02

Locations

1 site across 1 country: United States