NCT01518673

Low Dose Effects of X-rays in Pediatric Patients Undergoing a CT Examination.

National Study of Low Dose Effects of X-rays in Pediatric Patients Undergoing a CT Examination.

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 140 (actual)
• Sponsor: University Ghent · Academic / Other
• Sex: All
• Age: 12 Years
• Healthy volunteers: Not accepted

Summary

Patients undergoing a computed tomography are exposed to a relatively high dose of X-rays. Pediatric patients are known to be very radiosensitive with respect to radiation induced cancer. Using the technique of scoring γ-H2AX foci in peripheral blood lymphocytes the most important lesions to the genetic material DNA, double strand breaks induced by CT X-rays can be detected. The technique will be applied in a multicenter setting for evaluation of X-effects induced by a computed tomography examination in a population of pediatric patients. To this end a blood sample will be taken from the patients before and after the examination.

Conditions

• Pediatric Patients Undergoing a Computed Tomography Examination

Interventions

Type	Name	Description
PROCEDURE	Blood test	Analysing X-ray induced genetic effects in pediatric patients directly after a computer tomography scan.

Timeline

• Start date: 2012-02-01
• Primary completion: 2015-01-01
• Completion: 2015-06-01
• First posted: 2012-01-26
• Last updated: 2021-11-19

Locations

1 site across 1 country: Belgium