Clinical Trials Directory

Trials / Completed

CompletedNCT01516567

Intergroup Trial for Children or Adolescents With Primary Mediastinal Large B-Cell Lymphoma: DA-EPOCH-Rituximab Evaluation

Intergroup Trial for Children or Adolescents With B-Cell NHL or B-AL: Evaluation of Rituximab Efficacy and Safety in High Risk Patients - Phase II Trial of DA-EPOCH-Rituximab in PMLBL

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
47 (actual)
Sponsor
Gustave Roussy, Cancer Campus, Grand Paris · Academic / Other
Sex
All
Age
6 Months – 17 Years
Healthy volunteers
Not accepted

Summary

Phase II trial to determine the efficacy of Dose Adjusted-EPOCH-Rituximab regimen in children and adolescent with primary mediastinal large B cell lymphoma in terms of event free survival.

Conditions

Interventions

TypeNameDescription
DRUGEtoposide, Doxorubicin, Vincristine, Cyclophosphamide, Rituximab6 courses of Dose Adjusted-EPOCH-Rituximab Rituximab 375 mg/m² i.v.: one injection at each of the 6 courses of EPOCH.

Timeline

Start date
2012-04-01
Primary completion
2017-04-01
Completion
2022-11-16
First posted
2012-01-25
Last updated
2026-02-09

Locations

9 sites across 9 countries: Belgium, Canada, France, Hungary, Italy, Netherlands, Poland, Spain, United Kingdom

Source: ClinicalTrials.gov record NCT01516567. Inclusion in this directory is not an endorsement.

Intergroup Trial for Children or Adolescents With Primary Mediastinal Large B-Cell Lymphoma: DA-EPOCH-Rituximab Evaluati (NCT01516567) · Clinical Trials Directory