NCT01516437

A Study to Assess Immunity to Specific Microbial Antigens in Healthy Smokers and Non-smokers and in Subjects With Stable COPD

A Study to Assess Immunity to Specific Microbial Antigens in Healthy Smokers and Non-smokers and in Subjects With Stable Chronic Obstructive Pulmonary Disease (COPD) Aged Between 45-75 Years

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 73 (actual)
• Sponsor: GlaxoSmithKline · Industry
• Sex: All
• Age: 45 Years – 75 Years
• Healthy volunteers: Accepted

Summary

The present study aims to assess the natural immunity to specific microbial antigens in healthy subjects and in subjects with stable COPD aged between 45-75 years.

Conditions

• Respiratory Disorders

Interventions

Type	Name	Description
PROCEDURE	Blood collection	Blood collection at Day 0 (all subjects) and at Month 6 (COPD subjects) for the analysis of serology, cell-mediated immune response.
PROCEDURE	Swab collection	Nasopharyngeal and oropharyngeal swabs collection at Day 0 (All subjects) and at exacerbation visits (COPD subjects).
PROCEDURE	Sputum collection	Sputum collection at Day 0 and at exacerbation visits (COPD subjects)

Timeline

• Start date: 2012-02-01
• Primary completion: 2012-06-28
• Completion: 2012-12-20
• First posted: 2012-01-24
• Last updated: 2017-05-17
• Results posted: 2017-03-07

Locations

3 sites across 1 country: Belgium