NCT01514539

Hormonal Regulation of Postpartum Weight and Presence of Gut Peptides in Human Milk

Role of Ghrelin and PYY in Postpartum Body Weight Regulation and Presence in Human Milk

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 44 (actual)
• Sponsor: University of Wyoming · Academic / Other
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

Hormonal Regulation of Postpartum Weight and Presence of Gut Peptides in Human Milk Studies suggest that childbearing is an important contributor to the development of obesity in many women and that breastfeeding may be protective. Ghrelin and peptide YY (PYY) are gut hormones involved in appetite regulation and energy homeostasis and are biological neuroendocrine signals that potentially affect body weight and adiposity/

Detailed description

Role of Ghrelin and PYY in Postpartum Body Weight Regulation and Presence in Human Milk. This study evaluated whether fasting or postprandial ghrelin or PYY is different between lactating and nonlactating postpartum women matched for age, body weight, and adiposity. Eligibility Criteria: Healthy females, 18+ years old, non-smokers, no major food allergies, first-time mom, currently pregnant or within 1 month of giving birth.

Conditions

• Maternal Obesity Syndrome

Interventions

Type	Name	Description
OTHER	cross-sectional	Monitoring two recently discovered appetite hormones called "ghrelin" and "neuropeptide YY (PYY)." This study evaluated whether fasting or postprandial ghrelin or PYY is different btween lactating and nonlactating postpartum women matched for age, body weight, and adiposity.

Timeline

• Start date: 2009-08-01
• Primary completion: 2014-04-01
• Completion: 2014-04-01
• First posted: 2012-01-23
• Last updated: 2015-01-09

Locations

1 site across 1 country: United States