NCT01512524

Hormonal Deficiency in the Quality of Life of Patients With Traumatic Brain Injury

Long Term Follow-up of Moderate and Severe Traumatic Bain Injury and Assessment of Involvement of Hormonal Deficiency in the Quality of Life

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 88 (actual)
• Sponsor: Hospices Civils de Lyon · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The primary objective is to assess the long-term impact of hormonal deficiency on Quality of Life (QoL) in a large group of moderate and severe Traumatic Brain Injury (TBI) patients.

Detailed description

Severe Traumatic Brain Injury, when not leading to mortality, is a major cause of morbidity in early adulthood. Recent studies have demonstrated a previously unappreciated association between Severe Traumatic Brain Injury and endocrine dysfunction. The current trial aims at evaluating the quality of life 18 months post-trauma and associating this outcome to growth hormone levels.

Conditions

• Traumatic Brain Injury (TBI)

Interventions

Type	Name	Description
OTHER	MRI scan and endocrinology analysis	Endocrinology analysis including statique and dynamic exams, neuropsychologic evaluations and IRM scan.

Timeline

• Start date: 2011-11-23
• Primary completion: 2017-05-01
• Completion: 2017-05-01
• First posted: 2012-01-19
• Last updated: 2025-12-19

Locations

1 site across 1 country: France