NCT01512121

Spinal Cord Stimulation and Functional MRI

Investigating the Cortical Correlates of Spinal Cord Stimulation Using Functional Magnetic Resonance Imaging

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 10 (actual)
• Sponsor: Vibhor Krishna · Academic / Other
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Not accepted

Summary

The overall objective of this study is to assess patterns of fMRI cortical activation with spinal cord stimulation (SCS) in patients with neuropathic leg pain and therefore define cortical correlates, as well as to investigate cortical representations of pain and pain relief and the interactions therein, in the setting of neuropathic leg pain and SCS.

Detailed description

The main objective is to define, using functional magnetic resonance imaging, the effects of spinal cord stimulation (SCS) on cortical and subcortical BOLD effects in patients with neuropathic leg pain. Our hypothesis is that SCS will demonstrate a consistent pattern of BOLD activation that will correlate with symptomatic improvement.

Conditions

• Complex Regional Pain Syndrome (CRPS)
• Neuropathic Leg Pain

Timeline

• Start date: 2011-09-01
• Primary completion: 2017-08-01
• Completion: 2017-08-01
• First posted: 2012-01-19
• Last updated: 2019-09-23

Locations

1 site across 1 country: United States