Clinical Trials Directory

Trials / Completed

CompletedNCT01511133

Serological Response to Porcine Circovirus Type 1 (PCV-1) and PCV-1 DNA in Stools of Infants Following Administration of Rotarix™

Blinded Retrospective Laboratory Evaluations to Assess the Serologic Response to Porcine Circovirus Type 1 (PCV-1) and PCV-1 DNA in the Stool of Infants Aged 6 to 12 Weeks Following Administration of GlaxoSmithKline (GSK) Biologicals' Oral Live Attenuated Human Rotavirus Vaccine (444563)

Status
Completed
Phase
Study type
Observational
Enrollment
1 (actual)
Sponsor
GlaxoSmithKline · Industry
Sex
All
Age
6 Weeks – 12 Weeks
Healthy volunteers
Not accepted

Summary

This study aims to test the clinical samples (stool and serum) previously collected during clinical development of HRV vaccine, to identify if there is any evidence of PCV-1 replication and/or immune response to the PCV-1 in vaccinated infants.

Detailed description

Serum and stool samples collected from 4 clinical trials previously conducted for HRV vaccine (Rotarix™) are used in this study.

Conditions

Interventions

TypeNameDescription
PROCEDUREStool sampleStool samples collected at pre-determined time points in previous studies will be analysed to detect the presence of PCV-1 DNA and pattern of detection.
PROCEDURESerum sampleSerum samples collected at pre and post vaccination time points in previous studies will be assessed for Anti-PCV-1 antibody.

Timeline

Start date
2010-04-01
Primary completion
2010-06-01
Completion
2010-06-01
First posted
2012-01-18
Last updated
2017-05-16

Source: ClinicalTrials.gov record NCT01511133. Inclusion in this directory is not an endorsement.