NCT01510977

Second Bowel Preparation for Colonoscopy Failure

The Outcome of a Second Preparation for Colonoscopy After Preparation Failure in the First Procedure: a Prospective Randomized Controlled Study

• Status: Terminated
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 150 (actual)
• Sponsor: Asan Medical Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Colonoscopy is a basic but important tool to diagnose and treat lesions of the colon. Proper colon cleansing is essential for colonoscopy to be performed with a good quality. Inadequate bowel preparation leads to longer colonoscopic insertion time and patient discomfort, as well as inadequate diagnostic yield of colonic lesions. Frequency of colonoscopy failure due to bad bowel preparation is reported to be 0.3% to 6.5 percent, and the rate increases with liver cirrhosis, constipation, dementia, stroke, or administration of tricyclic antidepressants. In case of colonoscopy failure due to bad bowel preparation, the second colonoscopy can be performed with either adding a colon cleansing solution immediately, or it can be performed after a few days with colon cleansing agent together with prokinetics. These different kinds of bowel preparations after first colonoscopy failure have not been compared.

Conditions

• Colonoscopy Failure
• Poor Bowel Preparation

Interventions

Type	Name	Description
DRUG	polyethylene glycol, Bisacodyl	After failure of first colonoscopy, bowel preparation with polyethylene glycol and bisacodyl one week after
DRUG	polyethylene glycol	Immediately after first colonoscopy failure, polyethylene glycol 2L addition

Timeline

• Start date: 2011-11-01
• Primary completion: 2013-02-01
• Completion: 2013-02-01
• First posted: 2012-01-18
• Last updated: 2013-02-13

Locations

1 site across 1 country: South Korea