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No Longer AvailableNCT01510431

Safety and Treatment Outcome Study of PROCHYMAL® (Remestemcel-L) Intravenous Infusion in Subjects With Treatment-resistant Crohn's Disease

An Open-label Compassionate Treatment Protocol to Evaluate the Safety and Treatment Outcomes of PROCHYMAL® (Remestemcel-L) Intravenous Infusion in Subjects With Treatment-resistant Crohn's Disease

Status
No Longer Available
Phase
Study type
Expanded Access
Enrollment
Sponsor
Mesoblast, Inc. · Industry
Sex
All
Age
18 Years – 70 Years
Healthy volunteers
Not accepted

Summary

Protocol 620 provides PROCHYMAL(R) adult human mesenchymal cells to specifically chosen Crohn's disease patients at participating centers who typically have already demonstrated good response in another PROCHYMAL study, are not eligible for other PROCHYMAL studies, and in the view of the investigator, would not benefit significantly from other Crohn's therapies but would benefit from use of PROCHYMAL. The study is not placebo-controlled or randomized.

Conditions

Interventions

TypeNameDescription
DRUGPROCHYMAL (remestemcel-L)intravenous administration of 200 million cells on days 0, 3, 7, and 14, and then, at investigator discretion, periodically thereafter

Timeline

First posted
2012-01-16
Last updated
2020-03-10

Locations

4 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT01510431. Inclusion in this directory is not an endorsement.

Safety and Treatment Outcome Study of PROCHYMAL® (Remestemcel-L) Intravenous Infusion in Subjects With Treatment-resista (NCT01510431) · Clinical Trials Directory