Clinical Trials Directory

Trials / Completed

CompletedNCT01505647

Safety and Immunogenicity of Zoster Vaccine (ZOSTAVAX™) Made With an Alternative Manufacturing Process (AMP) (V211-042 AM1)

A Phase III Double-Blinded, Randomized, Multicenter, Controlled Study to Evaluate the Safety, Tolerability, and Immunogenicity of ZOSTAVAX™ Made With an Alternative Manufacturing Process (AMP)

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
498 (actual)
Sponsor
Merck Sharp & Dohme LLC · Industry
Sex
All
Age
50 Years
Healthy volunteers
Accepted

Summary

This study will determine whether ZOSTAVAX™ made with an alternative manufacturing process \[ZOSTAVAX™ (AMP)\] is well tolerated and immunogenic, and has a comparable immune response to ZOSTAVAX™.

Conditions

Interventions

TypeNameDescription
BIOLOGICALZoster Vaccine, Live (AMP)One approximately 0.65-mL injection subcutaneously on Day 1
BIOLOGICALZoster Vaccine, LiveOne approximately 0.65-mL injection subcutaneously on Day 1

Timeline

Start date
2012-04-01
Primary completion
2012-07-01
Completion
2012-11-01
First posted
2012-01-06
Last updated
2017-04-12
Results posted
2013-07-03

Source: ClinicalTrials.gov record NCT01505647. Inclusion in this directory is not an endorsement.