NCT01504607

Corneal Endothelial Changes Following Pediatric Cataract Surgery With IOL Implantation

Corneal Endothelial Morphologic Assessment in Pediatric Cataract Surgery With IOL Implantation: Comparison of Preoperative and Early Postoperative Specular Microscopy

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 106 (actual)
• Sponsor: Iladevi Cataract and IOL Research Center · Academic / Other
• Sex: All
• Age: 4 Years – 15 Years
• Healthy volunteers: Not accepted

Summary

Cataract surgery is known to cause loss of corneal endothelial cells. In adults, it is reported that anywhere between 2 to 15% loss of corneal endothelial cell density occurs following cataract surgery. However, no data is available regarding endothelial changes after cataract surgery with IOL implantation in pediatric eyes. The aim of this study is to prospectively observe changes in endothelial cell density, coefficient of variation and hexagonality following cataract surgery with IOL implantation in pediatric eyes.

Conditions

• Congenital Cataract Surgery
• IOL Implantation
• Change in Corneal Endothelial Cell Morphology

Interventions

Type	Name	Description
PROCEDURE	Congenital Cataract Surgery	Congenital cataract surgery with IOL implantation

Timeline

• Start date: 2011-01-01
• Primary completion: 2011-10-01
• Completion: 2011-10-01
• First posted: 2012-01-05
• Last updated: 2012-01-05