NCT01502748

Endovascular Magnesium Sampling in Acute Stroke

Magnesium Therapy: a Novel Platform for Neuroprotectant Sampling in Acute Stroke

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 2 (actual)
• Sponsor: University of Southern California · Academic / Other
• Sex: All
• Age: 40 Years – 95 Years
• Healthy volunteers: Not accepted

Summary

This investigation will address the safety and feasibility of distal, intra-arterial sampling through endovascular access, in acute stroke patients. Levels of Magnesium will be measured in the region of infarct in patients who had been treated with intravenous Magnesium therapy following an acute stroke. This study attempts to address whether the traditional intravenous means of neuroprotectant administration achieves adequate concentration of the therapeutic agent in the area of diseased tissue.

Conditions

• Acute Stroke

Interventions

Type	Name	Description
OTHER	endovascular sampling	Paired sampling from the distal arterial(endovascular catheter) and peripheral venous (femoral sheath) locations: withdrawal of 3ml of blood from vasculature distal to the occlusive thrombus

Timeline

• Start date: 2012-03-01
• Primary completion: 2013-02-01
• Completion: 2013-02-01
• First posted: 2012-01-02
• Last updated: 2017-08-01

Locations

2 sites across 1 country: United States