NCT01499641

Epidural Steroid Following Discectomy for Herniated Disc Reduces Morbidity

Epidural Steroid Following Discectomy for Herniated Lumbar Disc Reduces Neurological Impairment and Enhances Recovery. A Randomized Study With Two-year Follow-up

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (actual)
• Sponsor: Northern Orthopaedic Division, Denmark · Academic / Other
• Sex: All
• Age: 18 Years – 66 Years
• Healthy volunteers: Not accepted

Summary

Focus of this study is evaluation of the outcome, neurologic impairment and safety of epidural steroide following lumbar discectomy for herniated disc disease.

Detailed description

Methylprednisolone might enhance recovery after discectomy for herniated disc disease without apparent side effect. Convalescence after discectomy for herniated disc disease is dependent on pain and the inflammatory response. In arthroscopic and abdominal surgery steroids reduce the inflammatory response and enhance recovery. 200 patients with herniated disc disease are randomly allocated to receive epidural methylprednisolone 40 mg or none.

Conditions

• Disc Disease

Interventions

Type	Name	Description
DRUG	Methylprednisolone	Epidural methylprednisolone 40 mg or none

Timeline

• Start date: 2001-05-01
• Primary completion: 2003-08-01
• Completion: 2005-12-01
• First posted: 2011-12-26
• Last updated: 2014-09-15

Locations

3 sites across 1 country: Denmark