NCT01497951

Photodynamic Therapy for Oral Precursor Lesions

A Randomized Controlled Trial: Photodynamic Treatment for the Therapy of Premalignant Mucosal Oral Lesions.

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 28 (actual)
• Sponsor: Medical University of Vienna · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Pre-malignant lesions are difficult to treat. Even after surgical removal they tend to re-appear. Often the lesions are to large and are apparent on many sites, therefore surgical removal is not always possible. The photodynamic therapy uses a special substance, which is absorbed in cells, and thereafter activated by a defined light. The aim of this study is to compare the photodynamic therapy in potentially malignant lesions to a placebo. The investigators assume a significant better result in photodynamic therapy then treatment with a placebo.

Conditions

• Leukoplakia
• Lichen

Interventions

Type	Name	Description
OTHER	Aminolaevulinic acid	Photodynamic therapy
OTHER	Methylcellulose Placebo	Methylcellulose

Timeline

• Start date: 2011-05-01
• Primary completion: 2017-01-01
• Completion: 2017-01-01
• First posted: 2011-12-23
• Last updated: 2017-05-17

Locations

1 site across 1 country: Austria