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CompletedNCT01497652

A Double Blind Placebo Controlled Trial Evaluating Rasagiline Effects on Cognition in Parkinson's Disease Patients With Mild Cognitive Impairment Receiving Dopaminergic Therapy

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
34 (actual)
Sponsor
Georgetown University · Academic / Other
Sex
All
Age
40 Years
Healthy volunteers
Not accepted

Summary

The present pilot study is designed to assess the extent to which rasagiline may improve cognition in Parkinson's disease patients requiring dopaminergic therapy. The primary objective is to assess improvement in the Montreal Cognitive Assessment (MoCA) in patients who have been on rasagiline at 1mg daily for twelve weeks. The secondary objective is to assess changes in the SCOPA-COG, FAB, and UPDRS II \& III at the end of week 14.

Conditions

Interventions

TypeNameDescription
DRUGRasagiline/PlaceboWill receive placebo pills each day for the entire 14 weeks.
DRUGRasagiline0.5 mg for two weeks, then 1 mg for 12 weeks.

Timeline

Start date
2012-01-01
Primary completion
2015-03-01
Completion
2015-03-01
First posted
2011-12-22
Last updated
2015-12-16

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT01497652. Inclusion in this directory is not an endorsement.

A Double Blind Placebo Controlled Trial Evaluating Rasagiline Effects on Cognition in Parkinson's Disease Patients With (NCT01497652) · Clinical Trials Directory