NCT01496196

The Role of Inhalations of Tranexamic Acid in Patients With Hemoptysis

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Meir Medical Center · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

Hemoptysis is defined as the expectoration of blood from respiratory tract, a spectrum that varies from blood-streaking of sputum to coughing up large amounts of pure blood. Massive hemoptysis variably defined as the expectoration of 100-600 ml over 24-h period. The most common site of bleeding is the tracheobronchial tree, which can be affected by inflammation (acute or chronic bronchitis, bronchiectasis) or by neoplasm ( bronchogenic carcinoma, endobronchial metastatic carcinoma, bronchial carcinoid tumor). The bronchial arteries, which originate either from aorta or from intercostal arteries, and are part of the high-pressure systemic circulation, are the source of bleeding in bronchitis or bronchiectasis or endo bronchial tumors.

Conditions

• Hemoptisis

Interventions

Type	Name	Description
DRUG	tranexamic acid	500 mg/5 ml 3-4 times a day
DRUG	tranexamic acid	500 mg/5 ml 3-4 times a day

Timeline

• Start date: 2012-01-01
• Primary completion: 2016-01-01
• Completion: 2016-02-01
• First posted: 2011-12-21
• Last updated: 2015-04-14

Locations

1 site across 1 country: Israel