NCT01495143

Surgical Stress Measured by Microdialysis

Microdialysis of Paraspinal Muscle in Healthy Volunteers and Patients Underwent Posterior Lumbar Fusion Surgery

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 16 (actual)
• Sponsor: Northern Orthopaedic Division, Denmark · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Paraspinal muscle damage is inevitable during conventional posterior lumbar fusion surgery. Minimal invasive surgery is postulated to result in less muscle damage and better outcome. The aim of this study is to monitor metabolic changes of the paraspinal muscle and to evaluate paraspinal muscle damage during surgery using microdialysis (MD).

Detailed description

Posterior approach is a common and important surgical procedure for various lumbar diseases. Owing to the anatomy, the damage of paraspinal muscle is inevitable during conventional posterior lumbar fusion surgery. Degeneration and malfunction of the paraspinal muscle might associate with pain and inferior postoperative clinical outcome.

Conditions

• Trauma

Interventions

Type	Name	Description
PROCEDURE	Posterolateral lumbar fusion surgery	Two MD catheters with 1% lidocaine 1-2 ml are placed in the paraspinal muscle.

Timeline

• Start date: 2007-01-01
• Primary completion: 2007-12-01
• Completion: 2008-06-01
• First posted: 2011-12-19
• Last updated: 2014-09-15