Clinical Trials Directory

Trials / Completed

CompletedNCT01493817

Biomarkers in Samples From Younger Patients With Wilms Tumor

Observational - Relationships Between Tumor-Associated Macrophages and Clinicopathological Factors in Wilms Tumor

Status
Completed
Phase
Study type
Observational
Enrollment
30 (actual)
Sponsor
Children's Oncology Group · Network
Sex
All
Age
Healthy volunteers
Not accepted

Summary

This research study is studying biomarkers in tissue samples from younger patients with Wilms tumor. Studying samples of tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer. It may also help doctors predict how patients respond to treatment

Detailed description

PRIMARY OBJECTIVES: I. To determine whether recruitment of tumor-associated macrophages is related to clinicopathological factors in Wilms tumor (tumor stage, presence of vascular invasion, tumor progression, and survival). OUTLINE: Paraffin-embedded specimens are analyzed for macrophage markers. Results of each sample are then compared with patient's tumor stage, presence of vascular invasion, tumor progression, and survival.

Conditions

Interventions

TypeNameDescription
OTHERlaboratory biomarker analysisCorrelative studies

Timeline

Start date
2011-12-01
Primary completion
2016-05-01
First posted
2011-12-16
Last updated
2016-05-19

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT01493817. Inclusion in this directory is not an endorsement.