NCT01493297

Effects of Vitamin A and Carotenoids on Iron Absorption

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 25 (actual)
• Sponsor: Swiss Federal Institute of Technology · Academic / Other
• Sex: Female
• Age: 18 Years – 52 Years
• Healthy volunteers: Accepted

Summary

The objective of this study is to investigate the effect of vitamin A and carotenoids on iron absorption in healthy subjects with low and normal vitamin A status. Vitamin A and carotenoids have been reported to enhance the nonheme iron absorption, but the results from human isotope studies are equivocal. Radio-iron studies in Venezuelan adults have consistently reported an increase in iron absorption, whereas stable and radio isotopes studies conducted in Sweden and Switzerland reported no influence. Differences in vitamin A status of the subjects may be a possible explanation for the contradictory findings. In this study, iron absorption will be measured from an iron-fortified maize bread meal with or without retinyl palmitate or β-carotene by using both stable- and radioactive-isotope techniques in Venezuelan women with a range of vitamin A status.

Conditions

• Iron Absorption

Interventions

Type	Name	Description
OTHER	Labeled iron solutions	Labeled iron as FeSO4 (4 mg/test meal)

Timeline

• Start date: 2011-09-01
• Primary completion: 2011-11-01
• Completion: 2012-07-01
• First posted: 2011-12-15
• Last updated: 2014-01-23

Locations

1 site across 1 country: Venezuela