NCT01493206

A Prospective Single Arm Study of Intraoperative Radiotherapy for Locally Advanced or Recurrent Rectal Cancer

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 32 (actual)
• Sponsor: Peter MacCallum Cancer Centre, Australia · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The hypothesis is that intraoperative radiotherapy for locally advanced or recurrent rectal cancer improve outcomes without causing significant side effects.

Detailed description

Primary Outcome measures are 3-year locoregional control, progression-free and overall survival rates. Secondary outcome measures are toxicities scores up to 3 months after surgery (acute) and greater than 3 months after surgery (late). Data collected at 3-6 month intervals for 30 months

Conditions

• Malignant Rectal Neoplasm
• Recurrent Tumor

Interventions

Type	Name	Description
RADIATION	intraoperative radiotherapy	intraoperative radiotherapy

Timeline

• Start date: 2004-07-01
• Primary completion: 2011-08-01
• Completion: 2011-08-01
• First posted: 2011-12-15
• Last updated: 2025-05-31

Locations

1 site across 1 country: Australia