NCT01491165

Safety and Efficacy of Stem Cell Transplantation for Treatment of Liver Cirrhosis

Safety and Efficacy of Umbilical Cord Mesenchyma Stem Cell Transplantation in Liver Cirrhosis Patients

• Status: Unknown
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 75 (estimated)
• Sponsor: General Hospital of Chinese Armed Police Forces · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

Mainstream of current treatment of liver cirrhosis is liver transplantation, but there are high cost, risk and immune rejection and other issues. Umbilical cord mesenchyma stem cell with self-and directed differentiation capacity can effectively rescue experimental liver failure and contribute to liver regeneration, which suggests the feasibility of stem cell transplantation therapy. In this study, the safety and efficacy of umbilical cord mesenchyma stem cell transplantation through interventional procedures in patients liver cirrhosis will be evaluated.

Detailed description

This study included three research centers, each center were carried out 25 cases of liver cirrhosis in patients with stem cell transplantation. All the selection and exclusion criteria are same, data summary and analysis will be complete by the epidemiological commissioner.

Conditions

• Other Surgical Procedures

Interventions

Type	Name	Description
PROCEDURE	stem cell transplantation through interventional procedures	one time interventional procedures

Timeline

• Start date: 2011-12-01
• Primary completion: 2012-12-01
• Completion: 2014-06-01
• First posted: 2011-12-13
• Last updated: 2012-10-26

Locations

1 site across 1 country: China