NCT01490515

Embryo Selection Using Non-invasive Metabolomic Analysis Versus Morphology

Embryo Selection Using Non-invasive Metabolomic Analysis Indicates Improvement in Implantation Rates With Fetal Cardiac Activity

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 125 (actual)
• Sponsor: Eugonia · Academic / Other
• Sex: Female
• Age: 18 Years – 49 Years
• Healthy volunteers: Accepted

Summary

Metabolomics was recently introduced in human IVF for non-invasive identification of viable embryos with the highest developmental competence. The investigators intended to investigate if embryo assessment using non-invasive metabolomic profiling leads to increased implantation rates compared to routine morphology evaluation alone.

Detailed description

Metabolomics was recently introduced in human IVF for non-invasive identification of viable embryos with the highest developmental competence. The aim of the present study was to determine whether embryo selection using non-invasive metabolomic profiling as an adjunct to morphology leads to increased implantation rates compared to routine morphology evaluation alone.

Conditions

• Embryo Viability

Interventions

Type	Name	Description
PROCEDURE	non-invasive metabolomic profiling	non-invasive metabolomic profiling of IVF human embryos
OTHER	morphological evaluation	Simple microscopic observation of embryos and evaluation of morphological characteristics

Timeline

• Start date: 2010-04-01
• Primary completion: 2010-12-01
• Completion: 2010-12-01
• First posted: 2011-12-13
• Last updated: 2013-12-16

Locations

1 site across 1 country: Greece