NCT01489683

Intubating Conditions During Propofol-remifentanil Anesthesia With Topical Lidocaine

Effect of Tracheal Lidocaine on Intubating Conditions During Propofol-remifentanil TCI Without Neuromuscular Blockade

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: Ajou University School of Medicine · Academic / Other
• Sex: All
• Age: 20 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

When not using neuromuscular blocking agent, even at optimal dosage, target-controlled infusion (TCI) of propofol and remifentanil occasionally produce unsatisfactory intubating conditions. Therefore, the investigators evaluated that the effect of tracheal lidocaine on the intubating conditions for tracheal intubation during anesthesia induction of propofol and remifentanil TCI without neuromuscular blocking agent in day-case anesthesia.

Detailed description

Anesthesia was induced with propofol-remifentanil TCI with the effect-site concentration of 5μg/ml and 5ng/ml, respectively. After TCI, 3 ml of normal saline or 3 ml of 4% lidocaine was instilled to larynx and trachea, following intubation was performed.

Conditions

• Drug Usage

Interventions

Type	Name	Description
DRUG	lidocaine	3 ml of 4% lidocaine was instilled to larynx and trachea
DRUG	normal saline	3 ml of normal saline was instilled to larynx and trachea before endotracheal intubation

Timeline

• Start date: 2011-05-01
• Primary completion: 2012-04-01
• Completion: 2012-05-01
• First posted: 2011-12-12
• Last updated: 2012-07-16

Locations

1 site across 1 country: South Korea