NCT01488396

Efficacy of 0.05% Cyclosporin Eye Drop in Stevens Johnson Syndrome Patient With Chronic Dry Eye

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 31 (actual)
• Sponsor: Mahidol University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate the efficacy of 0.05% cyclosporin ophthalmic emulsion (Restasis) in patients with Stevens-Johnson syndrome that have dry eyes by subjective symptoms and signs.

Detailed description

Stevens-Johnson syndrome patients in chronic stage who have dry eys symptoms and signs will be treated with 0.05%cyclosporin ophthalmic emulsion(Restasis)twice a day for 6 months, compare results at 0,2,4,6 months include dry eye symptoms, corneal staining (Fluorescein, Rose Bengal), Schirmer I,FCT and impression cytology

Conditions

• Stevens-Johnson Syndrome

Interventions

Type	Name	Description
DRUG	0.05%cyclosporin eye drop	use twice daily for 6 months

Timeline

• Start date: 2007-02-01
• Primary completion: 2009-07-01
• Completion: 2009-07-01
• First posted: 2011-12-08
• Last updated: 2011-12-08

Locations

1 site across 1 country: Thailand