NCT01485432

Goal Directed Hemodynamic Management and Renal Outcome After Renal Transplant Surgery

Can Goal Directed Hemodynamic Management Improve Renal Outcome After Renal Transplant Surgery?

• Status: Terminated
• Phase: —
• Study type: Observational
• Enrollment: 1 (actual)
• Sponsor: Technical University of Munich · Academic / Other
• Sex: All
• Age: 65 Years
• Healthy volunteers: Not accepted

Summary

This study is designed to compare the incidence of delayed graft function in patients following renal transplant surgery with different perioperative hemodynamic managements: a goal directed hemodynamic management group (using PiCCO) and a control group.

Detailed description

Volume assessment and management during renal transplantation is one of the most challenging problems the anesthetist has to deal with. It seems sensible that individualized volume management and hydration therapy during the operation and during the stay at the intensive care unit could improve perfusion of the transplanted organ resulting in a better transplant function. Aim of this study is to investigate the impact of a goal directed hemodynamic management on incidence of delayed graft function (DGF) after renal transplant surgery. Therefore patients will be randomized in one of two groups, the PiCCO group with goal directed hemodynamic management during operation and during the ICU-stay and the control group with hemodynamic management performed according to heart rate, blood pressure and central venous pressure.

Conditions

• Renal Transplant Surgery

Interventions

Type	Name	Description
DEVICE	PiCCO® Monitoring	Fluid and vasopressor management according to PiCCO measurements

Timeline

• Start date: 2011-10-01
• Primary completion: 2012-10-01
• Completion: 2019-10-01
• First posted: 2011-12-05
• Last updated: 2020-01-14

Locations

1 site across 1 country: Germany