NCT01485380

Combined Electroencephalogram, Magnetic Resonance Imaging-Positron Emission Tomography of Dexmedetomidine Induced Sleep

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Massachusetts General Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

The investigators are doing this research study to find out how and where dexmedetomidine, a sedative anesthetic, acts in the brain. The investigators will do this by using a machine that records the brains electrical activity, called an electroencephalogram (EEG), and brain imaging scans to look at the brain.

Conditions

• Dexmedetomidine Induced Sedation

Interventions

Type	Name	Description
DRUG	dexmedetomidine	The dexmedetomidine infusion will be individualized to each study participant by a target plasma concentration where loss of consciousness is initially observed. Loss of consciousness will be assayed by specific auditory and verbal stimuli.

Timeline

• Start date: 2012-09-01
• Primary completion: 2013-07-01
• Completion: 2013-07-01
• First posted: 2011-12-05
• Last updated: 2019-01-08
• Results posted: 2014-10-10

Locations

1 site across 1 country: United States