NCT01485367

A Pilot Study to Evaluate The Efficacy of Adapalene 0.3% for Use in the Prevention and Treatment of Senile Purpura

Phase II Pilot Study to Evaluate The Efficacy of Adapalene 0.3% for Use in The Prevention and Treatment of Senile Purpura

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Multispecialty Aesthetic Clinical Research Organization · Academic / Other
• Sex: All
• Age: 52 Years
• Healthy volunteers: Accepted

Summary

This is an open label 6 month pilot study for male and female participants over the age of 52 that desire treatment and prevention of senile purpura of the forearms. This study will be evaluating the effects of Adapalene 0.3% for the use in the treatment and prevention of senile purpura.

Detailed description

This is a new potential use for the product Adapalene 0.3%, which is currently an FDA approved topical treatment used for the treatment of acne. Senile purpura is a common sign of aging that appears in the form of dark blotches on the skin and is caused by bruising. Older adults tend to be more prone to bruising, since as people age, their skin becomes thinner and more fragile.

Conditions

• Senile Purpura

Interventions

Type	Name	Description
DRUG	adapalene gel 0.3%	A pea size drop of Adapalene gel 0.3% will be applied to the odd numbered subjects on the left dorsal hand \& extensor forearm. A pea size drop of Adapalene gel 0.3% will be applied to the even numbered subjects on the right dorsal hand \& extensor forearm. The randomized area will be cleansed with Cetaphil Gentle Cleanser before applying the study medication. All subjects will apply sunscreen with zinc oxide in the morning to both the right \& left forearms.

Timeline

• Start date: 2011-12-01
• Primary completion: 2012-12-01
• Completion: 2012-12-01
• First posted: 2011-12-05
• Last updated: 2012-04-23

Locations

2 sites across 1 country: United States