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Trials / Completed

CompletedNCT01484561

A Study To Evaluate The Effect Of CP-690,550 On Measures Of Kidney Function In Patients With Active Rheumatoid Arthritis

A Phase 1, Randomized, Placebo-Controlled, Two-Period, Fixed Sequence Study To Evaluate The Effect Of CP-690,550 On Measured Glomerular Filtration Rate In Patients With Active Rheumatoid Arthritis

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
148 (actual)
Sponsor
Pfizer · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of study is to explore the effect of CP-690,550 (Tofacitinib) on measures of kidney function in patients with active rheumatoid arthritis (RA).

Conditions

Interventions

TypeNameDescription
DRUGCP-690,550 or PlaceboCP-690,550 10 mg twice a day (BID) orally or placebo BID orally, approximately 72 days
DRUGPlaceboPlacebo BID orally, approximately 72 days

Timeline

Start date
2012-04-01
Primary completion
2013-01-01
Completion
2013-02-01
First posted
2011-12-02
Last updated
2014-04-02
Results posted
2014-04-02

Locations

24 sites across 8 countries: United States, Czechia, Germany, Mexico, Poland, Russia, South Korea, Spain

Source: ClinicalTrials.gov record NCT01484561. Inclusion in this directory is not an endorsement.

A Study To Evaluate The Effect Of CP-690,550 On Measures Of Kidney Function In Patients With Active Rheumatoid Arthritis (NCT01484561) · Clinical Trials Directory