Clinical Trials Directory

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UnknownNCT01484171

HLA-mismatched Microtransplantation for High Risk Acute Myeloid Leukemia

Status
Unknown
Phase
Phase 3
Study type
Interventional
Enrollment
50 (estimated)
Sponsor
The Affiliated Hospital of the Chinese Academy of Military Medical Sciences · Academic / Other
Sex
All
Age
7 Years – 60 Years
Healthy volunteers
Not accepted

Summary

To compare the antitumor efficacy and toxicity of Idarubicin and cytarabine in combination with or not with infusions of granulocyte colony-stimulating factor-mobilized HLA-mismatched donor peripheral blood stem cells in patients with newly diagnosed high-risk acute myeloid leukemia (AML).

Conditions

Interventions

TypeNameDescription
DRUGidarubicinidarubicin 10-12 mg/m2 for three days
BIOLOGICALmicrotransplantationidarubicin 10-12mg/m2 for four days. After chemotherapy infusion granulocyte colony-stimulating factor-mobilized HLA-mismatched donor peripheral blood stem cells following each of three cycles of high dose cytarabine chemotherapy

Timeline

Start date
2011-08-01
Primary completion
2017-08-01
Completion
2017-12-01
First posted
2011-12-02
Last updated
2016-07-13

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT01484171. Inclusion in this directory is not an endorsement.