NCT01480752

Reduction of Post-operative Endodontic Pain

the Effect of Intraligamentary Injection of Lornoxicam on the Intensity of Post-operative Endodontic Pain in the Tooth With Symptomatic Irreversible Pulpitis

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Islamic Azad University, Sanandaj · Academic / Other
• Sex: All
• Age: 16 Years – 65 Years
• Healthy volunteers: Accepted

Summary

To determine the effect of intraligamentary injection of Lornoxicam on the intensity of post-operative endodontic pain in the tooth with symptomatic irreversible pulpitis.

Detailed description

sixty qualified samples (initial estimate which will be come more accurate after the pilot study on 6 patients) will be divided randomly in three groups which all of them will have an inferior Alveolar injection and before the beginning of the treatment the primary group will receive an injection of 0.4 mL ( 0.2 mL in mesio buccal and 0.2 mL in disto buccal) of Lornoxicam and the second group will be injected with 0.4 mL of normal saline( 0.2 mL in mesio buccal and 0.2 mL in disto buccal) ,in third group we will only pretend the injection but actually there is no substance injected ,making the patient believe that there was an injection . Then the patients' pain will be evaluated with visual Analogue Scale analysis (VAS) 0-170 mm in time intervals of 6, 12, 24 and 48 hours after the treatment.

Conditions

• Post Operative Endodontic Pain

Interventions

Type	Name	Description
DRUG	Lornoxicam	PDL injection of 0/2 ml of lornoxicam (4mg/ml),before the root therapy and after the inferior alveolar injection
DRUG	normal saline	PDl injection of 0/2 ml normal saline before the root therapy and after inferior alveolar injection
DRUG	no injection	inject nothing after inferior alveolar injection and before root canal therapy

Timeline

• Start date: 2011-09-01
• Primary completion: 2012-09-01
• Completion: 2012-12-01
• First posted: 2011-11-29
• Last updated: 2013-01-14

Locations

1 site across 1 country: Iran