NCT01480687

Fish Oil Supplementation and Vascular Function in Hypertensive Patients With Hypertriglyceridemia

Effects of Fish Oil Supplementation on Vascular Structure and Function in Hypertensive Patients With Hypertriglyceridemia

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 52 (estimated)
• Sponsor: Hospital Universitario Pedro Ernesto · Academic / Other
• Sex: All
• Age: 40 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The objective of this study is to compare the effects of ciprofibrate versus omega-3 fatty acid supplementation on the vascular structure and function in hypertensive patients with hypertriglyceridemia.

Detailed description

Hypertensive patients aged 40-65 years, both genders, presenting serum triglycerides levels higher than 150 mg/dl will be randomized into two groups. The first group will be receiving ciprofibrate 100mg/day and the second group will be receiving fish oil 1800mg/day. All patients will be evaluated with brachial flow-mediated dilation and with EndoPAT to assess endothelial function before and after supplementation. SPHYGMOCOR and pulse wave velocity (PWV) measurements will also be obtained.

Conditions

• Hypertension
• Hypertriglyceridemia

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	DHA-EPA	1800 mg/day
DRUG	Ciprofibrate	100 mg/day

Timeline

• Start date: 2011-05-01
• Primary completion: 2012-12-01
• Completion: 2012-12-01
• First posted: 2011-11-29
• Last updated: 2011-11-29

Locations

1 site across 1 country: Brazil