NCT01479751

Comparison of Methods to Facilitate Rapid Sequence Intubation

Comparison of Mg, Ketamine, Large Dose Rocuronium, and Priming on Intubating Condition in Rapid Sequence Intubation

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 110 (actual)
• Sponsor: Seoul National University Bundang Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

In this study, methods which are known for facilitating rapid sequence intubation or accelerating rocuronium (Roc)onset are compared including magnesium (Mg), ketamine pretreatment, large dose rocuronium and priming.

Detailed description

Patients are pretreated with Mg, ketamine, or priming dose Roc. Two groups do not receive pretreatment, but are given Roc 0.6 mg/kg or 0.9 mg/kg.

Conditions

• Intubating Condition

Interventions

Type	Name	Description
DRUG	Magnesium Sulfate	Patients receive MgSO4 50 mg/kg for 10 min before injection of Roc 0.6 mg/kg.
DRUG	Ketamine	patients receive ketamine 0.5 mg/kg 2 min before Roc injection.
DRUG	rocuronium	Patients receive Roc 0.06 mg/ kg as a priming dose 3 min before injection of Roc 0.54 mg/kg.

Timeline

• Start date: 2011-11-01
• Primary completion: 2012-05-01
• Completion: 2012-08-01
• First posted: 2011-11-24
• Last updated: 2012-08-27

Locations

1 site across 1 country: South Korea