Clinical Trials Directory

Trials / Completed

CompletedNCT01478373

Efficacy and Safety of Dovitinib in Patients With Gastrointestinal Stromal Tumors Refractory and/or Intolerant to Imatinib

DOVIGIST: Phase II Trial to Evaluate the Efficacy and Safety of Dovitinib (TKI258) in Patients With Gastrointestinal Stromal Tumors Refractory and/or Intolerant to Imatinib

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
39 (actual)
Sponsor
Novartis Pharmaceuticals · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the efficacy and safety of Dovitinib in patients with gastrointestinal stromal tumors refractory and/or intolerant to Imatinib

Conditions

Interventions

TypeNameDescription
DRUGDovitinib (TKI258)Oral Dovitinib (TKI258) as a gelatin capsule of 100 mg strength and dosed on a flat scale of 500 mg on a 5 days on /2 days off dosing schedule.

Timeline

Start date
2012-01-01
Primary completion
2014-07-01
Completion
2014-07-01
First posted
2011-11-23
Last updated
2016-04-27
Results posted
2015-08-10

Locations

15 sites across 5 countries: Finland, France, Germany, Italy, Spain

Source: ClinicalTrials.gov record NCT01478373. Inclusion in this directory is not an endorsement.