NCT01476449

Dosing Study of Ranibizumab for Diabetic Retinal and Macular Edema

Monthly Ranibizumab Versus Treat and Extend Ranibizumab for Diabetic Macular Edema

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Retina Vitreous Associates of Florida · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This study is to see whether treating diabetic retinal swelling with ranibizumab injections into the eye monthly is better than treating diabetic retinal swelling with ranibizumab injections into the eye less frequently.

Detailed description

This is a prospective randomized study comparing two groups of patients with diabetic macular edema. One group will receive injections of ranibizumab monthly and the other group will have the option to receive injections of ranibizumab less frequently. That is eligible to receive the injections less frequently will have fewer injections given if the patients in that group are doing well.

Conditions

• Diabetic Retinopathy
• Macular Edema

Interventions

Type	Name	Description
DRUG	Ranibizumab	Pars plana injection of ranibizumab 0.5mg into the vitreous cavity.
DRUG	Ranibizumab	Pars plana injection of ranibizumab 0.5mg into the vitreous cavity.

Timeline

• Start date: 2011-11-01
• Primary completion: 2016-09-01
• Completion: 2016-09-01
• First posted: 2011-11-22
• Last updated: 2019-05-17
• Results posted: 2019-05-17

Locations

2 sites across 1 country: United States