Trials / Completed
CompletedNCT01476280
Palonosetron Versus Ramosetron for the Prevention of Postoperative Nausea and Vomiting
A Randomized Double Blind Study to Evaluate Efficacy of Ramosetron and Palonosetron for Prevention of Postoperative Nausea and Vomiting After Gynaecological Laparoscopic Surgery
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 100 (actual)
- Sponsor
- Incheon St.Mary's Hospital · Academic / Other
- Sex
- Female
- Age
- 20 Years
- Healthy volunteers
- Not accepted
Summary
Ramosetron and palonosetron are more recently developed 5-hydroxytryptamine type 3 receptor antagonists and this randomized double blind study was designed to compare efficacy of ramosetron and palonosetron to prevent postoperative nausea and vomiting. Investigator hypothesized that palonosetron would have stronger and longer lasting antiemetic effect compared with ramosetron and evaluated the patients for the first 48 hours after surgery.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | palonosetron | 0.075mg immediately before induction of anesthesia |
| DRUG | Ramosetron | 0.3mg immediately before induction of anesthesia |
Timeline
- Start date
- 2011-05-01
- Primary completion
- 2011-08-01
- Completion
- 2011-08-01
- First posted
- 2011-11-22
- Last updated
- 2011-11-22
Locations
1 site across 1 country: South Korea
Source: ClinicalTrials.gov record NCT01476280. Inclusion in this directory is not an endorsement.