NCT01475708

Doxycycline in Therapy of Erythema Migrans

Doxycycline in Therapy of Erythema Migrans - do the Accompanying Symptoms Influence the Outcome?

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 400 (actual)
• Sponsor: University Medical Centre Ljubljana · Academic / Other
• Sex: All
• Age: 15 Years
• Healthy volunteers: Accepted

Summary

The investigators will compare the outcome of three groups of erythema migrans patients treated with doxycycline: a group without any accompanying symptoms, with mild symptoms and with severe symptoms that require lumbar puncture.

Detailed description

Patients with erythema migrans treated with doxycycline for two weeks will be followed-up for one year (at 2 weeks, 2, 6 and 12 months) clinically and also by filling in the questionnaire to assess the presence of certain symptoms. Also the control group of their friends or relatives without a history of Lyme borreliosis will be included. The presence of their (unspecific) symptoms will also be recorded by the questionnaire at the time of enrollment and at 6 and 12 months.

Conditions

• Lyme Borreliosis

Interventions

Type	Name	Description
DRUG	Doxycycline	100 mg PO bid, 14 days

Timeline

• Start date: 2011-05-01
• Primary completion: 2014-10-01
• Completion: 2014-11-01
• First posted: 2011-11-21
• Last updated: 2016-03-24

Locations

1 site across 1 country: Slovenia